Corning surfaces

For more than 30 years, Corning’s culture dishes have been modified with corona electric discharge and vacuum plasma technologies to create better surfaces for the growth of adherent cells. New cultivation technologies, such as tissue engineering and stem cells, require new surfaces with new capabilities. Corning’s investments in the development of surface modification technologies pave the way for new applications in cell culture, and this is the truth that introduces Corning as the first and only reliable name in the production of surfaces with guaranteed performance. Vandatab is proud to have cooperated with this company for years, officially as the only representative of Corning, it has been able to present a very large part of the wide range of products of this company in Iran to the specialists of this area.

Surfaces to increase cell adhesion

Corning’s CellBIND® product technology

CellBIND technology is Corning’s unique surface that uses a microwave process to combine a significant amount of oxygen on the cell culture surface, preparing the surface for cell attachment in difficult conditions.

Cell adaptation to low serum or serum-free conditions at maximum speed

Improving efficiency and attachment of cells to the surface

No need for any special handling or maintenance conditions

Corning laboratory products and equipment with Synthemax ™ surfaces

Corning’s Synthemax surface is designed to mimic the natural environment of cells, with an extracellular matrix derived from a peptide that promotes cell adhesion. This synthetic level enables the expansion and differentiation of embryonic stem cells for more than 20 consecutive passages in the vessel environment, which lacks any type of external or xeno-free agent and is accompanied by the following:

Stability of doubling time and cell viability

Preservation of expression of phenotypic markers such as Oct4, TRA-1-60, SSEA 4 and cell morphology

Maintain a normal karyotype

Preservation of pluripotency, determined by the formation of embryo-like bodies and teratomas

Directed cell differentiation into specific tissue types, such as cardiomyocytes

Corning Osteo Assay surface

The Corning Osteo Assay surface is designed for:

Direct assessment of osteoclast and osteoblast function in vitro

Differentiation of osteoclast and osteoblast precursor cells

Co-culture of osteoclasts or osteoblasts with other cell lines

Quantitative solution-based assays

Studies related to bone regeneration and pit formation

Corning microplates coated with poly-di-lysine (PDL)

Corning poly-di-lysine micropillets are covered by a layer of PDL (in the molecular weight range of 70 to 150 kDa, this layer gives the surface of the micropillet a net positive charge that improves the adhesion power of the cells).

Increase improvement of cell differentiation of primary nerve cells, glial cells and neuroblastomas

Increased adhesion of transfected cell lines, including HEK-293

Helping to attach cells during the assay process

Surfaces to reduce or inhibit cell adhesion

Surfaces with ultra-low adhesion (Ultra-Low) coated with Corning polystyrene

Ultra-low adhesive surfaces use a covalently bonded hydrogel layer to inhibit cell adhesion.

Cultivation of primary cultures of adult or tumor stem cells as non-adherent spheroids

Preventing attachment and division of surface dependent cells, such as fibroblasts

Strengthening the formation of embryo-like body from embryonic stem cells